Target controlled infusion of opioids for bariatric surgery and morphine loading dose

Target Controlled Infusion (TCI)

MORPHINE AND RELATED OPIOIDS History

first undisputed reference to "poppy juice" is found in the writings of Theophrastus in the third century B.C. the word opium being derived from the Greek word for "juice" the drug being obtained from the juice of the poppy Papaver sominiferum Arabian physicians were well versed in its uses and introduced the plant to the Orient Paracelsus, circa 1500, is credited with repopularising the drug i...

A background infusion of morphine enhances patient-controlled analgesia after cardiac surgery.

PURPOSE We compared the efficacy of patient-controlled analgesia (PCA), with or without a background infusion of morphine, on postoperative pain relief in patients extubated in the operating room after coronary artery bypass grafting (CABG) surgery. METHODS With Faculty Ethics approval, 60 consenting adults undergoing elective coronary artery surgery were randomly assigned to receive either m...

A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval

OBJECTIVE To evaluate the effects of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion on hemodynamic parameters, pain, sedation, and recovery score during oocyte retrieval. METHODS Sixty-nine women were scheduled for oocyte retrieval. Target-controlled propofol infusion at an effect-site concentration of 1.5 μg/mL was instituted. The pat...

Target-controlled infusion of propofol and remifentanil combined with dexmedetomidine reduces functional endoscopic sinus surgery bleeding.

The aim of the present study was to investigate the effects of target-controlled infusion (TCI) of propofol and remifentanil combined with dexmedetomidine on functional endoscopic sinus surgery (FESS) bleeding and surgical field. 62 patients scheduled to undergo FESS were randomly divided into experimental group (intravenous 0.5 µg kg-1 h-1 dexmedetomidine after 0.5 µg kg-1 bolus within 15 min ...